Acne is a difficult condition to treat. At present, the opted for treatments are the application of topical antiobiotics, antimicrobial and retinoid applications and oral retinoids and antibiotics. However, all these treatment procedures have some side effects. According to reports, a British drug company is conducting a phase I trial on an unnamed drug, already existing in the market, on 18 volunteers to determine if the excretion of sebum is reduced by it. Cipher Pharmaceuticals Inc.'s CIP-Isotretinoin for acne is going in for further trials pending FDA approval.

Now, according to a recent study conducted by the Department of Dermatology, Hammersmith Hospital, London, a non-antibiotic treatment may soon be available. The results of this study was published in the British Journal of Dermatology.

Study Highlights
a. Researchers studied 40 volunteers.
b. The volunteers were between the age of 16 and 45 and have mild to moderate acne.
c. All the volunteers were given random treatment either with the active lotion, containing triethyl citrate and ethyl linoleate, or with vehicle.
d. The treatment was given twice daily, for three months.
e. The skin was reviewed at 4, 8 and 12 weeks.
f. Researchers also measured the sebum production of the skin at the beginning and the end of the study.
g. It was seen that the volunteers treated with the active lotion reported significant improvement as compared to the vehicle.
h. They also reported a decrease in sebum production.
i. The effects also started showing after just 4 weeks of treatment.