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The new age dermal-fillers to eradicate wrinkles if approved by FDA may push temporary fillers into a thing of the past. The current fillers subsides the wrinkles for few months, but with the permanent fillers the results lasts for years. The ArteFill, (permanent filler) is pending before FDA for clearance. With the rise in America’s anti-aging obsession the demand for the fillers is growing. But the usage of long-lasting fillers has raised concerns among doctors, as they feel that no one knows how long lasting fillers will look years after as face continuous to age. The matter of concern is the old short-term fillers are made of natural products, but the long-lasting fillers are largely made of synthetic materials for durability.