According to a recent study conducted by Alexander Dagum, a plastic surgeon at Stony Brook University Hospital in New York state, US, injecting a person with collagenase, an enzyme that digests collagen, is a safe and effective method of treating cellulite. The study was conducted over a period of 6 weeks on 10 women.

Experiment Highlights
a. Ten participants agreed to undergo the study protocol.
b. All the participants were women in the mean age of 41 years.
c. Their mean body mass index (BMI) was 28.
d. All the participants had more than 10 x 10 cm of cellulite area in the posterolateral thigh.
e. Researchers took digital photographs of the treatment area.
f. All the participants were injected with 10,000 ABC units (0.58mg) of collagenase at five points in the treatment area.
g. Sterile 0.9 per cent NaCl and 2mM CaCl2 were used as the buffers.
h. Participants were given treatment on day 1, week 1, week 3, and month 6.
i. Post treatment photographs were taken serially.
j. 6 weeks after the first injection, participants were given the option of getting a similar collagenase injection on the other thigh for cosmetic symmetry.
k. All participants experienced significant reduction in cellulite in the treatment area.
l. Some participants experienced temporary tenderness in the injection area, ecchymosis and mild edema.