Medicis and Ipsen announced the approval of the Food and Drug Administration's of the United States of the Biologics License Application (BLA) for Dysport (abobotulinumtoxinA), an acetylcholine release inhibitor and a neuromuscular blocking agent. The approval includes the treatment of cervical dystonia in adults to reduce the severity of abnormal head position and neck pain and the temporary improvement in the appearance of moderate to severe glabellar lines in adults younger than 65 years of age. Medicis, known for their Restylane and Perlane facial fillers, will promote the Dysport brand as part of a US sales agreement with the manufacturer. The anticipated availability of Dysport for aesthetic use in the US during is 30 to 60 days.Physicians in the U.S. may place orders for DYSPORTTM for the aesthetic indication by calling 1-877-520-0500

Product Highlights
a. This product is derived from botulinum toxin.
b. It will be available in the United States within 60 days.
c. Dysport's label will include a boxed warning of the possibility that the botulinum toxins may spread.
d. Dysport is said to be faster-acting than botox in wrinkle removal and has a greater spread resulting in a more 'natural' look.
e. The use of Dysport also means fewer injections and longer lasting results.
f. Dysport-related questions can also be directed to Dr. Jeffrey Adelglass at skintastic@skintastic.com. Dr. Jeffrey Adelglass, M.D., F.A.C.S. serves on the medical advisory board for Dysport(TM)

a. This product should be administered in accordance with the labeling instructions.
b. The recommended dosage and frequency of administration should not be exceeded.
c. Patients with a neuromuscular disorder of the nerve-muscle junction may be at increased risk of side effects.
d. Patients who have surgical changes to their faces, drooping eyelid folds, deep facial scars or thick oily skin should avoid this product.
e. Patients already being treated with aminoglycosides or other agents interfering with neuromuscular transmission should be observed closely for symptoms consistent with botulinum toxin effects.
f. It is not recommended for children or pregnant women.

Side Effects
a. The most common side effects are nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, sinus inflammation and nausea.
b. The most common side effects associated with the treatment of cervical dystonia are muscular weakness, difficulty in swallowing, dry mouth, injection site discomfort, fatigue, headache, neck pain, musculoskeletal pain, hoarseness, injection site pain and eye disorders.