dermal-fillers.jpg There are numerous dermal fillers that have been approved by the FDA and many more which are expected to be approved later this year. People concerned about aging can now have many options for treating facial wrinkles. The cost of dermal filler greatly depends on the time it lasts, if a dermal filler treatments with longer-lasting effects (such as Radiesse and Sculptra) are costliest ($1,000 or more a treatment) and those which are shorter-lasting effect are the least expensive (about $350).

Here's a list of some approved fillers and a few that may soon be added:

Human collagen based dermal filler: Brands include CosmoDerm, CosmoPlast, Cymetra.

What is it made of: Purified natural substance from human tissue.
How long does it last: Two to six months.
Bottom line: Safe but fades fast; no allergy test required.

Bovine collagen based dermal filler: Brands include Zyderm and Zyplast.

What is it made of: Purified collagen from cows.
How long does it last: Two to six months.
Bottom line: Requires allergy test before treatment; fades fast.

Hyaluronic acid based dermal filler: Brands include Restylane, Juvederm, Hylaform.

What is it made of: Synthetic or animal versions of a natural substance found in the body's joints.
How long does it last: Depending on the product formulation, from six to 12 months.
Bottom line: More expensive than collagen but lasts longer; safe; rare allergic reactions.

Calcium hydroxy- lapatite microspheres dermal filler: Brand name Radiesse. Awaiting FDA approval but is used off-label.

What is it made of: Synthetic, biocompatible substance.
How long does it last: 12 to 18 months.
Bottom line: Longer-lasting but not permanent; can cause lumpiness.

Synthetic polylactic acid in microspheres dermal filler: Brand name Sculptra. It's approved for other purposes but also used off-label for wrinkles.

What is it made of: Synthetic, biocompatible substance.
How long does it last: Two years.
Bottom line: Longer-lasting but not permanent; may cause lumpiness and other problems if injected improperly.

Polymethyl- methacrylate microspheres suspended in bovine collagen dermal filler: Brand name ArteFill. Awaiting FDA approval.

What is it made of: Synthetic, biocompatible substance injected with bovine collagen.
How long does it last: Five years or more.
Bottom line:Considered permanent; requires allergy test; likely to be expensive; may cause lumpiness; problems may be permanent or require surgery to fix.